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Multisystem Inflammatory Syndrome Associated With Coronavirus Disease in Children: A Multi-centered Study in Belém, Pará, Brazil.

de Farias, Emmerson C F; Pedro Piva, Jefferson; de Mello, Mary L F M F; do Nascimento, Luciana M P P; Costa, Carina C; Machado, Mayara M M; Rodrigues, Thatiane da S; Carvalho, Railana D F P; Alves, Marília C B; Aires, Larisse F Q; Cotta, Marilia L M; Pedreira, Ana R G; Saraty, Salma B; Lima, Miriam C; Justino, Maria C A.

Pediatr Infect Dis J ; 39(11): e374-e376, 2020 11.

Article in English | MEDLINE | ID: covidwho-884870

ABSTRACT

We described the characteristics of 11 children with pediatric multisystem inflammatory syndrome-temporally associated with SARS-CoV-2. The main clinical indications for hospital admission were vasogenic toxic shock (n = 2), Kawasaki disease (n = 4), and Kawasaki disease shock syndrome (n = 5). The echocardiography findings were abnormal in 63% of cases. All patients had 2 or more organ dysfunctions, and the mortality rate was 18%.

Subject(s)

Coronavirus Infections/physiopathology , Pneumonia, Viral/physiopathology , Systemic Inflammatory Response Syndrome/virology , Adolescent , Betacoronavirus/isolation & purification , Brazil/epidemiology , COVID-19 , Child , Child, Preschool , Coronavirus Infections/diagnosis , Coronavirus Infections/mortality , Coronavirus Infections/virology , Female , Humans , Infant , Infant, Newborn , Male , Mortality , Mucocutaneous Lymph Node Syndrome/diagnosis , Mucocutaneous Lymph Node Syndrome/mortality , Mucocutaneous Lymph Node Syndrome/physiopathology , Pandemics , Pneumonia, Viral/diagnosis , Pneumonia, Viral/mortality , Pneumonia, Viral/virology , Prospective Studies , SARS-CoV-2 , Systemic Inflammatory Response Syndrome/diagnosis , Systemic Inflammatory Response Syndrome/mortality , Systemic Inflammatory Response Syndrome/physiopathology

ABSTRACT

Subject(s)

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